Herewith you will find our latest news from our going research activities towards UPSIDE’s technological breakthrough
Kick off our work
eFUS device with Ispta
Validation of CMOS
Prototype of full EBI
Evidence of safety and function in vivo
EEG decoding algorithms
Upsider final results
The 2024 IEEE Ultrasonics, Ferroelectrics, and Frequency Control Joint Symposium took place this September 2024 and the TU Delft team was there. This venue brought together experts to discuss the latest advancements in ultrasonics technology, covering topics such as imaging techniques, sensing applications, and innovations in medical therapies. It was a fantastic opportunity
We are thrilled to announce the launch of our brand-new second Newsletter! This exciting publication is designed with you in mind, delivering curated content and exclusive updates. Here’s a recap of what you can expect from UPSIDE’s Newsletters: Insightful Articles: Stay informed with thought-provoking articles and in-depth analyses. Project Updates:
Behavioral experiments with rat models of depression featuring both implantable focused ultrasound neurostimulation and electrical recording devices, ideally require light and compact electronics that can simultaneously control the implantable devices and relay information to and from a computer for the proper control of the experiments and data analysis. We have
The UPSIDE project has the overall goal of combining electrical recording and ultrasound stimulation for the treatment of depression, as a less invasive alternative to the more intrusive approach of deep brain stimulation. The overall system is designed to be portable, with the core consisting of an epidural focused ultrasound
Clinical depression is associated with dysfunctional neural networks that regulate mood, emotion and reward-orientated behaviours. Neuromodulation is a therapeutic strategy aiming to correct the activity of the pathological pathways that underpin the key symptoms. The current project aims to produce an implantable epidural brain interface (EBI) with low-intensity focused ultrasound
This work aims to provide stakeholders with an accessible overview of the project’s technological strides, and the implications of these developments for future research and applications. The primary objective of WP2 in UPSIDE is to enhance the resolution and efficacy of neurophysiological data acquisition. Traditional methods face challenges in spatial
UPSIDE explores the potential of non-invasive electroencephalography (EEG) as a neuroimaging technique to detect biomarkers for Major Depressive Disorder (MDD). EEG, measuring brain electrical activity through scalp electrodes, has gained attention for its ability to reveal patterns associated with depression. Abnormalities in alpha wave activity, alpha/beta ratio, frontal asymmetry, and
Great news! We’re thrilled to announce that our lunch presentations on the UPSIDE project keep going on. We’ve had some fantastic sessions so far, with each one building upon the last to deepen our understanding and push our research forward. Here’s a quick recap of the presentations made to date:
We are thrilled to announce the launch of our brand-new first Newsletter! This exciting publication is designed with you in mind, delivering curated content and exclusive updates right to your inbox. Here’s what you can expect from UPSIDE’s Newsletter: Insightful Articles: Stay informed with thought-provoking articles and in-depth analyses. Project
Last week, the 7 partners of UPSIDE met in Freiburg to celebrate the first on-site general assembly of the project after the kick off meeting. The meeting took place on 21 and 22 September at the premises of the Freiburg University. This was a perfect occasion to get to know each other
Responsive neuromodulation offers hope for patients with neuropsychiatric disorders, but progress is hindered by a disconnect between traditional materials and modern technology. Brain signaling relies heavily on ion flux, not electron movement. Unfortunately, current neural signal acquisition materials, like noble metals, interact only with electrons, leading to ion accumulation at
IEEE took place between 21-25 May 2023 & upside project was there. Our Article on titled: A Low-Power Oscillatory Feature Extraction Unit for Implantable Neural Interfaces presents a feature extraction unit for neural oscillatory synchrony that bypasses the phase extraction step to reduce hardware complexity. Power and area efficient on-chip
From March 2023 on, within UPSIDE we will organize ”Lunch presentations” where all partner’s organizations members will be invited. During those, PhD and Postdoc researchers from the TU Delft, the University of Ghent and the University of Freiburg will present in more depth what they are working on related to UPSIDE in order to promote
The EIC Summit took place on 7-8 December 2022 in Brussels. The key European deep-tech innovation event of the year, was bringing together start-ups, researchers, investors, policy makers and corporates. You can watch the plenaries of the event and presentation on the EIC Summit Website. UPSIDE was of-course thrilled to be there
In October 2022, more than 600 attendees from 23 countries gathered for the Foundation’s 8th International Symposium on Focused Ultrasound. The Symposium showcased the tremendous progress in the field. Before the meeting began, more than 200 prerecorded scientific presentations were made available to all attendees. The program featured four days of
We were very pleased to get together with all UPSIDERs in Delft, the Netherlands, on the 22 and 23 of September 2022 for our kick-off meeting. It was a great chance, to meet in person with everyone for a first time, introduce our teams and our work plan ahead for the next